Lake County, IL – Officials are warning residents about a potent synthetic opioid linked to rising overdose deaths.
According to the Lake County Coroner’s Office, a substance known as cyclorphine has been identified in regional drug supplies, including in nearby Chicago, and is believed to be contributing to an increase in fatal overdoses across the Midwest.
The coroner’s office said cyclorphine is significantly more potent than fentanyl, with even very small amounts capable of causing death. Officials also warned the drug may not be detectable on standard fentanyl test strips, increasing the risk for individuals who may unknowingly consume it.
Health officials added that overdoses involving cyclorphine may require multiple doses of naloxone, commonly known as Narcan, due to how the substance interacts with the brain.
Cyclorphine may appear in several forms, including off-white or gray powder, counterfeit pills resembling prescription medications such as oxycodone or hydromorphone, or mixed with other substances like heroin, methamphetamine, or xylazine without a user’s knowledge.
Authorities emphasized that illicit drugs and counterfeit pills pose serious and unpredictable dangers. Residents are urged to only take medications prescribed directly to them and dispensed by licensed pharmacies.
If an overdose is suspected, officials advise calling 911 immediately and administering Narcan if available. Rapid response can be life-saving.
The warning is particularly relevant for younger residents and students who may encounter counterfeit pills that resemble legitimate medications.
This article was produced by a journalist and may include AI-assisted input.
All content is reviewed for accuracy and fairness.
Follow us on Instagram & Facebook and support local independent news.
Have a tip? Message us.





