Cambridge, Massachusetts – Takeda Pharmaceuticals will lay off 242 employees at its Binney Street facility, triggering workforce reductions beginning May 26, 2026.
According to a Worker Adjustment and Retraining Notification (WARN) filing submitted to Massachusetts officials, the Cambridge-based company is implementing organizational changes that will result in job cuts across its U.S. operations, including its headquarters location.
The notice states that employee notifications began March 25, with transitions starting no sooner than late May. Some additional changes may continue into 2026 and 2027 depending on business needs and timing.
Takeda indicated that the cuts are part of a broader transformation effort affecting multiple functions. The filing estimates a combination of approximately 247 layoffs in Massachusetts and 387 in other states, though employees may have opportunities to apply for redeployment within the company’s global network.
The impacted worksite is listed as 500 Kendall Street in Cambridge, a major hub in the region’s biotechnology sector. The company noted that the decision is permanent and does not include “bumping rights,” meaning displaced workers will not automatically replace others in different roles.
Affected employees are expected to receive at least 60 days’ notice, along with severance packages, outplacement services, and potential internal job placement assistance.
For Cambridge’s workforce—particularly young professionals and biotech workers—the layoffs reflect ongoing shifts in the life sciences industry, where restructuring and cost adjustments continue to impact employment stability.
Takeda, headquartered in Japan, employs thousands globally and maintains a significant presence in Massachusetts’ life sciences corridor.
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