How tiny balls of human brain tissue are revealing the causes of childhood epilepsy — and possible treatments

Researchers used tiny balls of human brain tissue to study tuberous sclerosis complex, a genetic disorder that causes early-onset, often drug-resistant epilepsy. The findings identify cellular mechanisms behind abnormal brain activity and point to potential treatments that could reduce the need for surgery. The work may help explain why current drugs fail and guide future therapies for affected children.

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